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Title: Rare bioparticle detection via deep metric learning
Authors: Luo, Shaobo
Shi, Yuzhi
Chin, Lip Ket
Zhang, Yi
Wen, Bihan
Sun, Ying
Nguyen, Binh T. T.
Chierchia, Giovanni
Talbot, Hugues
Bourouina, Tarik
Jiang, Xudong
Liu, Ai-Qun
Keywords: Engineering::Electrical and electronic engineering
Issue Date: 2021
Source: Luo, S., Shi, Y., Chin, L. K., Zhang, Y., Wen, B., Sun, Y., Nguyen, B. T. T., Chierchia, G., Talbot, H., Bourouina, T., Jiang, X. & Liu, A. (2021). Rare bioparticle detection via deep metric learning. RSC Advances, 11(29), 17603-17610.
Journal: RSC Advances
Abstract: Recent deep neural networks have shown superb performance in analyzing bioimages for disease diagnosis and bioparticle classification. Conventional deep neural networks use simple classifiers such as SoftMax to obtain highly accurate results. However, they have limitations in many practical applications that require both low false alarm rate and high recovery rate, e.g., rare bioparticle detection, in which the representative image data is hard to collect, the training data is imbalanced, and the input images in inference time could be different from the training images. Deep metric learning offers a better generatability by using distance information to model the similarity of the images and learning function maps from image pixels to a latent space, playing a vital role in rare object detection. In this paper, we propose a robust model based on a deep metric neural network for rare bioparticle (Cryptosporidium or Giardia) detection in drinking water. Experimental results showed that the deep metric neural network achieved a high accuracy of 99.86% in classification, 98.89% in precision rate, 99.16% in recall rate and zero false alarm rate. The reported model empowers imaging flow cytometry with capabilities of biomedical diagnosis, environmental monitoring, and other biosensing applications.
ISSN: 2046-2069
DOI: 10.1039/D1RA02869C
Schools: School of Electrical and Electronic Engineering 
Rights: © 2021 The Author(s). Published by the Royal Society of Chemistry. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:EEE Journal Articles

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