Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/152804
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dc.contributor.authorBonassi, Andreaen_US
dc.contributor.authorCataldo, Ilariaen_US
dc.contributor.authorGabrieli, Giulioen_US
dc.contributor.authorLepri, Brunoen_US
dc.contributor.authorEsposito, Gianlucaen_US
dc.date.accessioned2021-10-06T08:27:57Z-
dc.date.available2021-10-06T08:27:57Z-
dc.date.issued2021-
dc.identifier.citationBonassi, A., Cataldo, I., Gabrieli, G., Lepri, B. & Esposito, G. (2021). Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships. Brain Sciences, 11(9), 1123-. https://dx.doi.org/10.3390/brainsci11091123en_US
dc.identifier.issn2076-3425en_US
dc.identifier.urihttps://hdl.handle.net/10356/152804-
dc.description.abstractHumans are evolutionary-driven to adult mating and conceive social expectations on the quality of their affiliations. The genetic susceptibility to adverse environments in critical periods can alter close relationships. The current research investigates how the promoter region of the Serotonin Transporter Gene (5-HTTLPR) and perceived caregiving behavior in childhood could influence the social expectations on close adult relationships. For this purpose, 5-HTTLPR data was collected from the buccal mucosa of 65 Italian individuals (33 males). The participants filled (a) the Parental Bonding Instrument (PBI) to provide the levels of care and overprotection from mother and father, and (b) the Experience in Close Relationships-Revised (ECR-R) to report the social expectations on the intimate relationship assessed in terms of anxiety and avoidance from the partner. An interaction effect between 5-HTTLPR and PBI dimensions on the ECR-R scores was hypothesized. Results confirmed that the interplay between the genetic groups and history of maternal overprotection predicted avoidance experienced in romantic relationships in adulthood. Moreover, both adult anxiety and avoidance felt in an intimate relationship were found to covary as a function of maternal overprotection. The present work proposes further evidence of the genetic and parental mechanisms regulating social expectations involved in close relationships.en_US
dc.description.sponsorshipMinistry of Education (MOE)en_US
dc.description.sponsorshipNanyang Technological Universityen_US
dc.language.isoenen_US
dc.relationM4081597en_US
dc.relationRG55/18en_US
dc.relation.ispartofBrain Sciencesen_US
dc.relation.uri10.21979/N9/SZNMRIen_US
dc.rights© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).en_US
dc.subjectSocial sciences::Psychologyen_US
dc.titleSerotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationshipsen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Social Sciencesen_US
dc.contributor.schoolLee Kong Chian School of Medicine (LKCMedicine)en_US
dc.identifier.doi10.3390/brainsci11091123-
dc.description.versionPublished versionen_US
dc.identifier.pmid34573145-
dc.identifier.scopus2-s2.0-85114036839-
dc.identifier.issue9en_US
dc.identifier.volume11en_US
dc.identifier.spage1123en_US
dc.subject.keywordsGene Environmenten_US
dc.subject.keywordsSerotonin Transporter Geneen_US
dc.description.acknowledgementThis research was supported by grants from the NAP SUG (M4081597, 2015-2021) and the Ministry of Education, Singapore, under its Academic Research Fund Tier 1 (RG55/18) to G.E.en_US
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