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Title: A perspective on the role of point-of-care "immuno-triaging" to optimize COVID-19 vaccination distribution in a time of scarcity
Authors: Zhang, Yi
Rogers, Angela
Nadeau, Kari
Gu, Jun
Yang, Samuel
Keywords: Engineering::Mechanical engineering
Issue Date: 2021
Source: Zhang, Y., Rogers, A., Nadeau, K., Gu, J. & Yang, S. (2021). A perspective on the role of point-of-care "immuno-triaging" to optimize COVID-19 vaccination distribution in a time of scarcity. Frontiers in Public Health, 9, 638316-.
Project: 203-A020001
Journal: Frontiers in Public Health
Abstract: Vaccine bears hope to bring COVID-19 pandemic under control. With limited supply, vaccines must be utilized efficiently to provide protection to those who need it most. Currently, no practical framework has been proposed to ensure fair vaccine allocation at individual level, which is a recognized problem. We propose here an evidence-based decision-making framework for COVID-19 vaccine appropriation that prioritizes vaccine doses to individuals based on their immunological status, or immuno-triaging. To ensure successful implementation of the proposed framework, point-of-care (POC) immunodiagnostic testing is needed to quickly ramp up the testing capability. Considerations for deploying POC immunodiagnostic testing at such a large scale are discussed. We hope that the proposed immunological decision-making framework for evidence-based COVID-19 vaccine appropriation provides an objective approach to ensure fair and efficient utilization of the scarce vaccine resource at the individual level that also maximizes the collective societal benefit.
ISSN: 2296-2565
DOI: 10.3389/fpubh.2021.638316
Rights: © 2021 Zhang, Rogers, Nadeau, Gu and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MAE Journal Articles

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