Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/153487
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dc.contributor.authorZhang, Nanen_US
dc.contributor.authorLai, Hui Yingen_US
dc.contributor.authorGautam, Archanaen_US
dc.contributor.authorYu, Darien De Kweken_US
dc.contributor.authorDong, Yibingen_US
dc.contributor.authorWang, Qiangen_US
dc.contributor.authorNg, Kee Woeien_US
dc.date.accessioned2021-12-12T06:01:39Z-
dc.date.available2021-12-12T06:01:39Z-
dc.date.issued2021-
dc.identifier.citationZhang, N., Lai, H. Y., Gautam, A., Yu, D. D. K., Dong, Y., Wang, Q. & Ng, K. W. (2021). An enzymatic method for harvesting functional melanosomes after keratin extraction – maximizing resource recovery from human hair. Journal of Polymers and the Environment. https://dx.doi.org/10.1007/s10924-021-02246-8en_US
dc.identifier.issn1566-2543en_US
dc.identifier.urihttps://hdl.handle.net/10356/153487-
dc.description.abstractHair contains about 80% keratins and 1–3% melanin packaged in melanosomes. Both of these are high-value and functional raw materials that have potential applications in wide-ranging fields. While keratin extraction has been widely refined, efficient methods of melanosome extraction are limited. The extraction of melanosomes requires complete removal of keratin, thus combining keratin extraction and melanosome isolation is logical. Herein, a successive process to harvest melanosomes after keratin extraction from human hair waste was developed. The yield of melanosomes was about 1.3% of the total hair mass. The structure of harvested melanosomes is well preserved based on surface morphology and interior ultrastructural observations using electron microscopy. The chemical structure, ultraviolet (UV)-filtering ability, and thermal stability of the melanosomes are examined to demonstrate preservation of native functions. Our strategy of combining melanosome isolation with keratin extraction is shown to be effective and significantly improves the total resource recovery efficiency from human hair waste.en_US
dc.description.sponsorshipAgency for Science, Technology and Research (A*STAR)en_US
dc.language.isoenen_US
dc.relationH17/01/a0/008en_US
dc.relationH17/01/a0/0L9en_US
dc.relationNSF of China 51673087en_US
dc.relationCSC 201906790039en_US
dc.relation.ispartofJournal of Polymers and the Environmenten_US
dc.rights© 2021 The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. This paper was published in Journal of Polymers and the Environment and is made available with permission of The Author(s).en_US
dc.subjectEngineering::Materials::Biomaterialsen_US
dc.titleAn enzymatic method for harvesting functional melanosomes after keratin extraction – maximizing resource recovery from human hairen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Materials Science and Engineeringen_US
dc.contributor.researchNanyang Environment and Water Research Instituteen_US
dc.identifier.doi10.1007/s10924-021-02246-8-
dc.description.versionAccepted versionen_US
dc.subject.keywordsHuman Hairen_US
dc.subject.keywordsResource Recoveryen_US
dc.description.acknowledgementThis research was supported by the Agency for Science, Technology and Research (A*STAR) under its Acne and Sebaceous Gland Program & Wound Care Innovation for the Tropics IAF-PP (Grant Nos. H17/01/a0/008 & H17/01/a0/0L9), the National Natural Science Foundation of China (Grant No. 51673087), and the China Scholarship Council (Grant No.201906790039 to N.Z.).en_US
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