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Title: An enzymatic method for harvesting functional melanosomes after keratin extraction – maximizing resource recovery from human hair
Authors: Zhang, Nan
Lai, Hui Ying
Gautam, Archana
Yu, Darien De Kwek
Dong, Yibing
Wang, Qiang
Ng, Kee Woei
Keywords: Engineering::Materials::Biomaterials
Issue Date: 2021
Source: Zhang, N., Lai, H. Y., Gautam, A., Yu, D. D. K., Dong, Y., Wang, Q. & Ng, K. W. (2021). An enzymatic method for harvesting functional melanosomes after keratin extraction – maximizing resource recovery from human hair. Journal of Polymers and the Environment.
Project: H17/01/a0/008 
NSF of China 51673087 
CSC 201906790039 
Journal: Journal of Polymers and the Environment 
Abstract: Hair contains about 80% keratins and 1–3% melanin packaged in melanosomes. Both of these are high-value and functional raw materials that have potential applications in wide-ranging fields. While keratin extraction has been widely refined, efficient methods of melanosome extraction are limited. The extraction of melanosomes requires complete removal of keratin, thus combining keratin extraction and melanosome isolation is logical. Herein, a successive process to harvest melanosomes after keratin extraction from human hair waste was developed. The yield of melanosomes was about 1.3% of the total hair mass. The structure of harvested melanosomes is well preserved based on surface morphology and interior ultrastructural observations using electron microscopy. The chemical structure, ultraviolet (UV)-filtering ability, and thermal stability of the melanosomes are examined to demonstrate preservation of native functions. Our strategy of combining melanosome isolation with keratin extraction is shown to be effective and significantly improves the total resource recovery efficiency from human hair waste.
ISSN: 1566-2543
DOI: 10.1007/s10924-021-02246-8
Rights: © 2021 The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. This paper was published in Journal of Polymers and the Environment and is made available with permission of The Author(s).
Fulltext Permission: embargo_20220821
Fulltext Availability: With Fulltext
Appears in Collections:MSE Journal Articles
NEWRI Journal Articles

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  Until 2022-08-21
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