Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/153545
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dc.contributor.authorMohammad Alfatahen_US
dc.contributor.authorWong, Jin Hueien_US
dc.contributor.authorKrishnan, Vidhya Gomathien_US
dc.contributor.authorLee, Yong Cheowen_US
dc.contributor.authorSin, Quan Fengen_US
dc.contributor.authorGoh, Corinna Jie Huien_US
dc.contributor.authorKong, Kiat Whyeen_US
dc.contributor.authorLee, Wei Tingen_US
dc.contributor.authorLewis, Jacquelineen_US
dc.contributor.authorHoon, Shawnen_US
dc.contributor.authorArumugam, Prakashen_US
dc.date.accessioned2021-12-08T02:44:04Z-
dc.date.available2021-12-08T02:44:04Z-
dc.date.issued2021-
dc.identifier.citationMohammad Alfatah, Wong, J. H., Krishnan, V. G., Lee, Y. C., Sin, Q. F., Goh, C. J. H., Kong, K. W., Lee, W. T., Lewis, J., Hoon, S. & Arumugam, P. (2021). TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae. BMC Biology, 19(1), 95-. https://dx.doi.org/10.1186/s12915-021-01030-3en_US
dc.identifier.issn1741-7007en_US
dc.identifier.urihttps://hdl.handle.net/10356/153545-
dc.description.abstractTarget of Rapamycin Complex 1 (TORC1) is a highly conserved eukaryotic protein complex that couples the presence of growth factors and nutrients in the environment with cellular proliferation. TORC1 is primarily implicated in linking amino acid levels with cellular growth in yeast and mammals. Although glucose deprivation has been shown to cause TORC1 inactivation in yeast, the precise role of TORC1 in glucose signaling and the underlying mechanisms remain unclear.en_US
dc.description.sponsorshipAgency for Science, Technology and Research (A*STAR)en_US
dc.language.isoenen_US
dc.relation.ispartofBMC Biologyen_US
dc.rights© 2021 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.en_US
dc.subjectScience::Biological sciencesen_US
dc.titleTORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiaeen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Biological Sciencesen_US
dc.contributor.organizationBioinformatics Instituteen_US
dc.contributor.organizationSingapore Institute for Food and Biotechnology Innovationen_US
dc.identifier.doi10.1186/s12915-021-01030-3-
dc.description.versionPublished versionen_US
dc.identifier.pmid33957926-
dc.identifier.scopus2-s2.0-85105155580-
dc.identifier.issue1en_US
dc.identifier.volume19en_US
dc.identifier.spage95en_US
dc.subject.keywordsTranscriptional Response to Glucoseen_US
dc.subject.keywordsTarget of Rapamycin Complex 1en_US
dc.description.acknowledgementWe would like to acknowledge A*STAR (Singapore)’s core funding provided to Bioinformatics Institute.en_US
item.grantfulltextopen-
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