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https://hdl.handle.net/10356/153545| Title: | TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae | Authors: | Mohammad Alfatah Wong, Jin Huei Krishnan, Vidhya Gomathi Lee, Yong Cheow Sin, Quan Feng Goh, Corinna Jie Hui Kong, Kiat Whye Lee, Wei Ting Lewis, Jacqueline Hoon, Shawn Arumugam, Prakash |
Keywords: | Science::Biological sciences | Issue Date: | 2021 | Source: | Mohammad Alfatah, Wong, J. H., Krishnan, V. G., Lee, Y. C., Sin, Q. F., Goh, C. J. H., Kong, K. W., Lee, W. T., Lewis, J., Hoon, S. & Arumugam, P. (2021). TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae. BMC Biology, 19(1), 95-. https://dx.doi.org/10.1186/s12915-021-01030-3 | Journal: | BMC Biology | Abstract: | Target of Rapamycin Complex 1 (TORC1) is a highly conserved eukaryotic protein complex that couples the presence of growth factors and nutrients in the environment with cellular proliferation. TORC1 is primarily implicated in linking amino acid levels with cellular growth in yeast and mammals. Although glucose deprivation has been shown to cause TORC1 inactivation in yeast, the precise role of TORC1 in glucose signaling and the underlying mechanisms remain unclear. | URI: | https://hdl.handle.net/10356/153545 | ISSN: | 1741-7007 | DOI: | 10.1186/s12915-021-01030-3 | Rights: | © 2021 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
| Appears in Collections: | SBS Journal Articles |
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| s12915-021-01030-3.pdf | 3.05 MB | Adobe PDF | View/Open |
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