Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/153545
Title: TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae
Authors: Mohammad Alfatah
Wong, Jin Huei
Krishnan, Vidhya Gomathi
Lee, Yong Cheow
Sin, Quan Feng
Goh, Corinna Jie Hui
Kong, Kiat Whye
Lee, Wei Ting
Lewis, Jacqueline
Hoon, Shawn
Arumugam, Prakash
Keywords: Science::Biological sciences
Issue Date: 2021
Source: Mohammad Alfatah, Wong, J. H., Krishnan, V. G., Lee, Y. C., Sin, Q. F., Goh, C. J. H., Kong, K. W., Lee, W. T., Lewis, J., Hoon, S. & Arumugam, P. (2021). TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae. BMC Biology, 19(1), 95-. https://dx.doi.org/10.1186/s12915-021-01030-3
Journal: BMC Biology
Abstract: Target of Rapamycin Complex 1 (TORC1) is a highly conserved eukaryotic protein complex that couples the presence of growth factors and nutrients in the environment with cellular proliferation. TORC1 is primarily implicated in linking amino acid levels with cellular growth in yeast and mammals. Although glucose deprivation has been shown to cause TORC1 inactivation in yeast, the precise role of TORC1 in glucose signaling and the underlying mechanisms remain unclear.
URI: https://hdl.handle.net/10356/153545
ISSN: 1741-7007
DOI: 10.1186/s12915-021-01030-3
Rights: © 2021 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
Fulltext Permission: open
Fulltext Availability: With Fulltext
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