Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/153678
Title: The Qcrb inhibitors TB47 and telacebec do not potentiate the activity of clofazimine in mycobacterium abscessus
Authors: Sorayah, Ria
Moraski, Garret C.
Barkan, Daniel
Pethe, Kevin
Keywords: Science::Medicine
Science::Biological sciences
Issue Date: 2021
Source: Sorayah, R., Moraski, G. C., Barkan, D. & Pethe, K. (2021). The Qcrb inhibitors TB47 and telacebec do not potentiate the activity of clofazimine in mycobacterium abscessus. Antimicrobial Agents and Chemotherapy, 65(12), e0096421-. https://dx.doi.org/10.1128/AAC.00964-21
Project: NRF-NRFI06-2020-0004
Journal: Antimicrobial Agents and Chemotherapy
Abstract: The antituberculosis drug telacebec is ineffective against Mycobacterium abscessus. A recent study suggested that TB47, a telacebec analogue, potentiated the efficacy of clofazimine against M. abscessus. Here, we report that TB47 not only is ineffective against M. abscessus in vitro but also does not potentiate the activity of clofazimine.
URI: https://hdl.handle.net/10356/153678
ISSN: 0066-4804
DOI: 10.1128/AAC.00964-21
Rights: © 2021 American Society for Microbiology. All Rights Reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:LKCMedicine Journal Articles
SBS Journal Articles

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