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https://hdl.handle.net/10356/153678| Title: | The Qcrb inhibitors TB47 and telacebec do not potentiate the activity of clofazimine in mycobacterium abscessus | Authors: | Sorayah, Ria Moraski, Garret C. Barkan, Daniel Pethe, Kevin |
Keywords: | Science::Medicine Science::Biological sciences |
Issue Date: | 2021 | Source: | Sorayah, R., Moraski, G. C., Barkan, D. & Pethe, K. (2021). The Qcrb inhibitors TB47 and telacebec do not potentiate the activity of clofazimine in mycobacterium abscessus. Antimicrobial Agents and Chemotherapy, 65(12), e0096421-. https://dx.doi.org/10.1128/AAC.00964-21 | Project: | NRF-NRFI06-2020-0004 | Journal: | Antimicrobial Agents and Chemotherapy | Abstract: | The antituberculosis drug telacebec is ineffective against Mycobacterium abscessus. A recent study suggested that TB47, a telacebec analogue, potentiated the efficacy of clofazimine against M. abscessus. Here, we report that TB47 not only is ineffective against M. abscessus in vitro but also does not potentiate the activity of clofazimine. | URI: | https://hdl.handle.net/10356/153678 | ISSN: | 0066-4804 | DOI: | 10.1128/AAC.00964-21 | Rights: | © 2021 American Society for Microbiology. All Rights Reserved. | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
| Appears in Collections: | LKCMedicine Journal Articles SBS Journal Articles |
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