Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/153866
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dc.contributor.authorMolton, James S.en_US
dc.contributor.authorLee, I. Russelen_US
dc.contributor.authorBertrand, Denisen_US
dc.contributor.authorDing, Yingen_US
dc.contributor.authorKalimuddin, Shirinen_US
dc.contributor.authorLye, David C.en_US
dc.contributor.authorNagarajan, Niranjanen_US
dc.contributor.authorGan, Yunn-Hwenen_US
dc.contributor.authorArchuleta, Sophiaen_US
dc.date.accessioned2021-12-16T07:08:11Z-
dc.date.available2021-12-16T07:08:11Z-
dc.date.issued2021-
dc.identifier.citationMolton, J. S., Lee, I. R., Bertrand, D., Ding, Y., Kalimuddin, S., Lye, D. C., Nagarajan, N., Gan, Y. & Archuleta, S. (2021). Stool metagenome analysis of patients with Klebsiella pneumoniae liver abscess and their domestic partners. International Journal of Infectious Diseases, 107, 1-4. https://dx.doi.org/10.1016/j.ijid.2021.04.012en_US
dc.identifier.issn1201-9712en_US
dc.identifier.urihttps://hdl.handle.net/10356/153866-
dc.description.abstractObjectives: Hypermucoviscous Klebsiella pneumoniae is an emerging cause of community-acquired liver abscess. The aim of this study was to investigate whether hypermucoviscous strains could be shared among households. Methods: The clinical K. pneumoniae isolates from a cohort of 24 patients with Klebsiella liver abscess were genotyped, and the stool metagenomes of the index patients and their cohabiting domestic partners were analyzed. Results: K. pneumoniae was identified in 33% of index patient stools, and one index patient's clinical isolate was identified in their domestic partner's stool. Conclusions: This could represent a transmission event or could represent exposure to a common environmental source. (C) 2021 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.en_US
dc.description.sponsorshipSingapore Infectious Diseases Initiative - National Medical Research Councilen_US
dc.language.isoenen_US
dc.relationSIDI/2016/0 03en_US
dc.relation.ispartofInternational Journal of Infectious Diseasesen_US
dc.rights© 2021 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-ncnd/4.0/).en_US
dc.subjectScience::Medicineen_US
dc.titleStool metagenome analysis of patients with Klebsiella pneumoniae liver abscess and their domestic partnersen_US
dc.typeJournal Articleen
dc.contributor.schoolLee Kong Chian School of Medicine (LKCMedicine)en_US
dc.contributor.organizationNational University of Singaporeen_US
dc.contributor.organizationNational Centre for Infectious Diseasesen_US
dc.contributor.organizationTan Tock Seng Hospitalen_US
dc.identifier.doi10.1016/j.ijid.2021.04.012-
dc.description.versionPublished versionen_US
dc.identifier.pmid33862216-
dc.identifier.scopus2-s2.0-85105269502-
dc.identifier.volume107en_US
dc.identifier.spage1en_US
dc.identifier.epage4en_US
dc.subject.keywordsKlebsiella Pneumoniaeen_US
dc.subject.keywordsLiver Abscessen_US
dc.description.acknowledgementThis work was supported by the Singapore Infectious Diseases Initiative (grant number SIDI/2016/003).en_US
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Appears in Collections:LKCMedicine Journal Articles
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