Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/153866
Title: Stool metagenome analysis of patients with Klebsiella pneumoniae liver abscess and their domestic partners
Authors: Molton, James S.
Lee, I. Russel
Bertrand, Denis
Ding, Ying
Kalimuddin, Shirin
Lye, David C.
Nagarajan, Niranjan
Gan, Yunn-Hwen
Archuleta, Sophia
Keywords: Science::Medicine
Issue Date: 2021
Source: Molton, J. S., Lee, I. R., Bertrand, D., Ding, Y., Kalimuddin, S., Lye, D. C., Nagarajan, N., Gan, Y. & Archuleta, S. (2021). Stool metagenome analysis of patients with Klebsiella pneumoniae liver abscess and their domestic partners. International Journal of Infectious Diseases, 107, 1-4. https://dx.doi.org/10.1016/j.ijid.2021.04.012
Project: SIDI/2016/0 03
Journal: International Journal of Infectious Diseases
Abstract: Objectives: Hypermucoviscous Klebsiella pneumoniae is an emerging cause of community-acquired liver abscess. The aim of this study was to investigate whether hypermucoviscous strains could be shared among households. Methods: The clinical K. pneumoniae isolates from a cohort of 24 patients with Klebsiella liver abscess were genotyped, and the stool metagenomes of the index patients and their cohabiting domestic partners were analyzed. Results: K. pneumoniae was identified in 33% of index patient stools, and one index patient's clinical isolate was identified in their domestic partner's stool. Conclusions: This could represent a transmission event or could represent exposure to a common environmental source. (C) 2021 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
URI: https://hdl.handle.net/10356/153866
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2021.04.012
Rights: © 2021 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-ncnd/4.0/).
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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