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dc.contributor.authorNair, Harikrishnan A. S.en_US
dc.contributor.authorSubramoni, Sujathaen_US
dc.contributor.authorPoh, Wee Hanen_US
dc.contributor.authorNabilah Taqiah Hasnuddinen_US
dc.contributor.authorTay, Martinen_US
dc.contributor.authorGivskov, Michaelen_US
dc.contributor.authorTolker-Nielsen, Timen_US
dc.contributor.authorKjelleberg, Staffanen_US
dc.contributor.authorMcDougald, Dianeen_US
dc.contributor.authorRice, Scott A.en_US
dc.identifier.citationNair, H. A. S., Subramoni, S., Poh, W. H., Nabilah Taqiah Hasnuddin, Tay, M., Givskov, M., Tolker-Nielsen, T., Kjelleberg, S., McDougald, D. & Rice, S. A. (2021). Carbon starvation of Pseudomonas aeruginosa biofilms selects for dispersal insensitive mutants. BMC Microbiology, 21(1), 255-.
dc.description.abstractBiofilms disperse in response to specific environmental cues, such as reduced oxygen concentration, changes in nutrient concentration and exposure to nitric oxide. Interestingly, biofilms do not completely disperse under these conditions, which is generally attributed to physiological heterogeneity of the biofilm. However, our results suggest that genetic heterogeneity also plays an important role in the non-dispersing population of P. aeruginosa in biofilms after nutrient starvation.en_US
dc.description.sponsorshipMinistry of Education (MOE)en_US
dc.description.sponsorshipNanyang Technological Universityen_US
dc.description.sponsorshipNational Research Foundation (NRF)en_US
dc.relation.ispartofBMC Microbiologyen_US
dc.rights© 2021 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated in a credit line to the data.en_US
dc.subjectScience::Biological sciencesen_US
dc.titleCarbon starvation of Pseudomonas aeruginosa biofilms selects for dispersal insensitive mutantsen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Biological Sciencesen_US
dc.contributor.schoolInterdisciplinary Graduate School (IGS)en_US
dc.contributor.researchSingapore Centre for Environmental Life Sciences and Engineering (SCELSE)en_US
dc.description.versionPublished versionen_US
dc.subject.keywordsBioflm Developmenten_US
dc.description.acknowledgementThe authors would like to acknowledge the fnancial support from National Research Foundation and Ministry of Education Singapore under its Research Centre of Excellence Program, a grant from the Singapore Ministry of Educa‑ tion (MOE2019-T2–1-050) and Nanyang Technological University for research scholarship for HASN. Funding was also provided through the Australian Research Council (DP140102192).en_US
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