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Title: Carbon starvation of Pseudomonas aeruginosa biofilms selects for dispersal insensitive mutants
Authors: Nair, Harikrishnan A. S.
Subramoni, Sujatha
Poh, Wee Han
Nabilah Taqiah Hasnuddin
Tay, Martin
Givskov, Michael
Tolker-Nielsen, Tim
Kjelleberg, Staffan
McDougald, Diane
Rice, Scott A.
Keywords: Science::Biological sciences
Issue Date: 2021
Source: Nair, H. A. S., Subramoni, S., Poh, W. H., Nabilah Taqiah Hasnuddin, Tay, M., Givskov, M., Tolker-Nielsen, T., Kjelleberg, S., McDougald, D. & Rice, S. A. (2021). Carbon starvation of Pseudomonas aeruginosa biofilms selects for dispersal insensitive mutants. BMC Microbiology, 21(1), 255-.
Project: MOE2019-T2-1-050 
Journal: BMC Microbiology 
Abstract: Biofilms disperse in response to specific environmental cues, such as reduced oxygen concentration, changes in nutrient concentration and exposure to nitric oxide. Interestingly, biofilms do not completely disperse under these conditions, which is generally attributed to physiological heterogeneity of the biofilm. However, our results suggest that genetic heterogeneity also plays an important role in the non-dispersing population of P. aeruginosa in biofilms after nutrient starvation.
ISSN: 1471-2180
DOI: 10.1186/s12866-021-02318-8
Rights: © 2021 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated in a credit line to the data.
Fulltext Permission: open
Fulltext Availability: With Fulltext
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