Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/155069
Title: Asymmetric domino heck arylation and alkylation of nonconjugated dienes : double C–F···sodium attractive noncovalent interaction
Authors: Zhu, Daoyong
Xu, Wenqiang
Pu, Maoping
Wu, Yun-Dong
Chi, Robin Yonggui
Zhou, Steve Jianrong
Keywords: Science::Chemistry
Issue Date: 2021
Source: Zhu, D., Xu, W., Pu, M., Wu, Y., Chi, R. Y. & Zhou, S. J. (2021). Asymmetric domino heck arylation and alkylation of nonconjugated dienes : double C–F···sodium attractive noncovalent interaction. Organic Letters, 23(18), 7064-7068. https://dx.doi.org/10.1021/acs.orglett.1c02457
Journal: Organic Letters
Abstract: Palladium catalyzes a domino Heck arylation and alkylation of nonconjugated cyclodienes to produce trans isomers of disubstituted cyclohexenes in exceptionally high enantiomeric ratios, reaching 100:1 to 200:1 in many cases. Importantly, the interactions of the two CF bonds of Josiphos and the sodium ion of malonates facilitates stereoselective allylic attack through DFT calculations and experiments. This is a new type of attractive noncovalent interactions found in organometallic catalysis.
URI: https://hdl.handle.net/10356/155069
ISSN: 1523-7060
DOI: 10.1021/acs.orglett.1c02457
Rights: © 2021 American Chemical Society. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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