Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/155086| Title: | Asymmetric reductive and alkynylative heck bicyclization of enynes to access conformationally restricted aza[3.1.0]bicycles | Authors: | Huang, Xiaolei Nguyen, Minh Hieu Pu, Maoping Zhang, Luoqiang Chi, Robin Yonggui Wu, Yun-Dong Zhou, Steve Jianrong |
Keywords: | Science::Chemistry | Issue Date: | 2020 | Source: | Huang, X., Nguyen, M. H., Pu, M., Zhang, L., Chi, R. Y., Wu, Y. & Zhou, S. J. (2020). Asymmetric reductive and alkynylative heck bicyclization of enynes to access conformationally restricted aza[3.1.0]bicycles. Angewandte Chemie International Edition, 59(27), 10814-10818. https://dx.doi.org/10.1002/anie.202000859 | Project: | AME IRG A1783c0010 | Journal: | Angewandte Chemie International Edition | Abstract: | Conformationally restricted azabicycles are becoming increasingly important in medicinal research. Asymmetric Heck bicyclization of enynes proceeds to give medicinally useful aza[3.1.0] and aza[4.1.0] bicycles with excellent enantioselectivity. The key organopalladium species after bicyclization can be trapped by silanes and terminal alkynes. | URI: | https://hdl.handle.net/10356/155086 | ISSN: | 1521-3773 | DOI: | 10.1002/anie.202000859 | Schools: | School of Physical and Mathematical Sciences | Rights: | This is the peer reviewed version of the following article: Huang, X., Nguyen, M. H., Pu, M., Zhang, L., Chi, R. Y., Wu, Y. & Zhou, S. J. (2020). Asymmetric reductive and alkynylative heck bicyclization of enynes to access conformationally restricted aza[3.1.0]bicycles. Angewandte Chemie International Edition, 59(27), 10814-10818, which has been published in final form at https://doi.org/10.1002/anie.202000859. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
| Appears in Collections: | SPMS Journal Articles |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Angewandte Chemie Intl Edit - 2020 - Huang - Asymmetric Reductive and Alkynylative Heck Bicyclization of Enynes to Access.pdf | 627.86 kB | Adobe PDF |  View/Open |
SCOPUSTM
Citations
20
17
Updated on Sep 22, 2023
Web of ScienceTM
Citations
20
16
Updated on Sep 28, 2023
Page view(s)
67
Updated on Sep 29, 2023
Download(s) 50
89
Updated on Sep 29, 2023
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.