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Title: Subsurface detection of hair follicles in alopecia areata using optical coherence tomography
Authors: Yow, Ai Ping
Lee, Wellington Zhengdao
Wong, Damon Wing Kee
Tey, Hong Liang
Keywords: Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics
Engineering::Chemical engineering
Issue Date: 2022
Source: Yow, A. P., Lee, W. Z., Wong, D. W. K. & Tey, H. L. (2022). Subsurface detection of hair follicles in alopecia areata using optical coherence tomography. Skin Research & Technology, 28(2), 379-381.
Project: NMRC/CSA-INV/0023/2017 
Journal: Skin Research & Technology 
Abstract: Alopecia areata (AA) is an autoimmune skin disorder that affects any hair-bearing areas and results in localized nonscarring hair loss. It can occur in individuals at any age regardless of ethnicity with a lifetime risk of 1–2%.1 The loss of hair is caused by perifollicular inflammation, which is associated with cytokines and chemokines released by T cells.2, 3 Although spontaneous regrowth is possible in 80% of patchy AA, full resolution is slow.4 Patients with AA can be treated with various treatment options including a topical or intralesional steroid. While intralesional steroid injection is more effective and frequently used, it requires repeated injections every 4–6 weeks. In addition, patients may experience discomfort caused by the needle pricks during injection and the presence of steroid-induced atrophy at the site of injection.
ISSN: 0909-752X
DOI: 10.1111/srt.13138
Rights: ©2022 The Authors. Skin Research and Technology published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:IDMxS Journal Articles
LKCMedicine Journal Articles
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