Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/156206
Title: 3D automated quantification of epidermal thickness and dermal heterogeneity in high-definition optical coherence tomography: Illustrative utility in morphea
Authors: Lim, Gim Hui
Yow, Ai Ping
Zhao, Xiahong
Wong, Damon Wing Kee
Tey, Hong Liang
Keywords: Engineering::Chemical engineering
Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics
Issue Date: 2021
Source: Lim, G. H., Yow, A. P., Zhao, X., Wong, D. W. K. & Tey, H. L. (2021). 3D automated quantification of epidermal thickness and dermal heterogeneity in high-definition optical coherence tomography: Illustrative utility in morphea. Skin Research & Technology, 27(5), 977-979. https://dx.doi.org/10.1111/srt.13005
Project: NMRC/CSA-INV/0023/2017
Journal: Skin Research & Technology
Abstract: Scleroderma is the most common form of fibrotic disease involving the skin, and the subtype that only affects the skin is known as morphea. The conventional investigation for cutaneous fibrotic diseases is skin biopsy, an invasive ex vivo procedure. Typically, another biopsy of adjacent normal skin is required for comparison, in order to visualize the excessive dermal collagen deposition. Optical coherence tomography has been shown to be useful in fibrotic skin disorders, in obtaining in vivo cross-sectional visualization.1-3 The high-definition optical coherence tomography (HD-OCT) (Skintell®) developed more recently allows imaging with an enhanced resolution of 3µm in both axial and lateral planes and has an imaging depth of 570 µm.
URI: https://hdl.handle.net/10356/156206
ISSN: 0909-752X
DOI: 10.1111/srt.13005
Rights: © 2021 John Wiley & Sons A/S. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:IDMxS Journal Articles
LKCMedicine Journal Articles

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