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Title: Cell membrane-coated electrospun fibers enhance keratinocyte growth through cell-type specific interactions
Authors: Chooi, Wai Hon
Dong, Quanbin
Low, Jeremy Zhi Yan
Yuen, Clement
Chin, Jiah Shin
Lin, Junquan
Ong, William
Liu, Quan
Chew, Sing Yian
Keywords: Engineering::Chemical engineering
Issue Date: 2021
Source: Chooi, W. H., Dong, Q., Low, J. Z. Y., Yuen, C., Chin, J. S., Lin, J., Ong, W., Liu, Q. & Chew, S. Y. (2021). Cell membrane-coated electrospun fibers enhance keratinocyte growth through cell-type specific interactions. ACS Applied Bio Materials, 4(5), 4079-4083.
Project: RG38/19
Journal: ACS Applied Bio Materials
Abstract: Although cell membrane-coated fiber scaffolds can be useful for regenerative medicine by presenting both cell surface antigens and topographical cues, it remains unknown whether changes in cellular behavior on cell membrane-coated scaffolds are due to specific cell-cell interactions. In this work, the effects of scaffold fiber diameters and surface charges on the cell membrane coating efficiency were explored. Furthermore, fibroblast membrane-coated scaffolds improved the growth of human keratinocytes as compared to red blood cell membrane-coated and plain scaffolds. These results suggest the biofunctionality of cell membrane-coated scaffolds and the specific cell-cell interactions that are preserved to modulate cellular response.
ISSN: 2576-6422
DOI: 10.1021/acsabm.1c00303
Rights: This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Applied Bio Materials, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:IGS Journal Articles
LKCMedicine Journal Articles
SBS Journal Articles
SCBE Journal Articles

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