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dc.contributor.authorLow, Perlie Li Huien_US
dc.identifier.citationLow, P. L. H. (2022). Study of the interaction between nanovesicles derived from bacteria and different pathogenic bacteria. Final Year Project (FYP), Nanyang Technological University, Singapore.
dc.description.abstractStreptococcus pneumoniae, Staphylococcus aureus and Klebsiella pneumoniae are the three major pathogens that cause multiple severe diseases including bacterial coinfection and superinfection in respiratory pandemics. Unfortunately, conventional treatments against these bacterial infections such as antibiotics were futile as the bacteria continue to develop resistance to them. Hence, many research studies have tried to create effective vaccines. However, Staphylococcus aureus and Klebsiella pneumoniae do not have any viable vaccine to date while Streptococcus pneumoniae vaccines have limited serotype coverage. Therefore, while vaccine development is still in progress, it is also an opportunity to create novel drug delivery to address the limitation of vaccines. Extracellular vesicles (EVs) have been identified as both potential drug delivery systems and components for vaccine development. However, EV production is time-consuming and costly. Hence, in this project, Bacterial Derived Nanovesicles (BDNs), which are mimetics of extracellular vesicles, are produced as cost-efficient and scalable alternatives. In addition, the project also explores the interaction between the three aforementioned pathogens and the BDNs derived from them. The project findings have shown interaction between the three pathogens and BDNs derived from them.en_US
dc.publisherNanyang Technological Universityen_US
dc.titleStudy of the interaction between nanovesicles derived from bacteria and different pathogenic bacteriaen_US
dc.typeFinal Year Project (FYP)en_US
dc.contributor.supervisorCzarny Bertrand Marcel Stanislasen_US
dc.contributor.schoolSchool of Materials Science and Engineeringen_US
dc.description.degreeBachelor of Engineering (Materials Engineering)en_US
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Appears in Collections:MSE Student Reports (FYP/IA/PA/PI)
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  Until 2024-05-09
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