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Title: Bioinspired calcium phosphate composites
Authors: Wong, Emily Kai Lin
Keywords: Engineering::Materials
Issue Date: 2022
Publisher: Nanyang Technological University
Source: Wong, E. K. L. (2022). Bioinspired calcium phosphate composites. Final Year Project (FYP), Nanyang Technological University, Singapore.
Abstract: Nacre-like composites, especially the ones with self-healing properties have attracted attention for their remarkable properties. To potentially replicate the structure and properties of bioinspired self-healing structural composites, we have fabricated self-healing gelatin-based hydrogels and calcium phosphate (CaP) bricks. Physical crosslinking (hydrogen and hydrophobic interactions) between gelatin and tannic acid (TA) demonstrates the self-healing and bioadhesive properties; that act as the interfacial soft layers of mortar. Cap such as hydroxyapatite is a major inorganic mineral, commonly found in our bones to facilitate bone reconstruction will be used to fabricate as bricks. However, the adhesiveness between the gelatin-TA hydrogel and CaP has never been studied. We tested the shear bond strength between gelatin-TA hydrogel and CaP via shear lap test and found it to be between 21.37 ± 4.2 kPa and 40.4 ± 9.0 kPa. According to our optical microscope and shear lap test results, we found that the mechanical properties of our gelatin-based hydrogel could be tuned by the TA concentration. The development of self-healing gelatin-based hydrogels that have strong bonding to CaPs will allow the construction of CaP composites with brick-and-mortar structures for biomedical applications.
Schools: School of Materials Science and Engineering 
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:MSE Student Reports (FYP/IA/PA/PI)

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