Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/158559
Title: Fibrillated bacterial cellulose liquid carbene bioadhesives for mimicking and bonding oral cavity surfaces
Authors: Singh, Juhi
Steele, Terry W. J.
Lim, Sierin
Keywords: Science::Medicine::Tissue engineering
Engineering::Materials::Biomaterials
Issue Date: 2022
Source: Singh, J., Steele, T. W. J. & Lim, S. (2022). Fibrillated bacterial cellulose liquid carbene bioadhesives for mimicking and bonding oral cavity surfaces. Journal of Materials Chemistry B, 10(14), 2570-2583. https://dx.doi.org/10.1039/d1tb02044g
Project: H19/01/a0/0II9 
MOE2018-T2-2-114 
Journal: Journal of Materials Chemistry B 
Abstract: Topical treatments for oral wounds and infections exhibit weak adhesion to wet surfaces which results in short retention duration (6-8 hours), frequent dosing requirement and patient incompatibility. To address these limitations, aqueous composites made of fibrillated bacterial cellulose and photoactive bioadhesives are designed for soft epithelial surfaces. The aqueous composites crosslink upon photocuring within a minute and exhibit a transition from viscous to elastic adhesive hydrogels. The light-cured composites have shear moduli mimicking oral mucosa and other soft tissues. The tunable adhesion strength ranges from 3 to 35 kPa on hydrated tissue-mimicking surfaces (collagen film). The results support the application of bacterial cellulose hydrogel systems for potential treatment of mucosal wounds.
URI: https://hdl.handle.net/10356/158559
ISSN: 2050-750X
DOI: 10.1039/d1tb02044g
Rights: © 2022 The Royal Society of Chemistry. All rights reserved. This paper was published in Journal of Materials Chemistry B and is made available with permission of The Royal Society of Chemistry.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:IGS Journal Articles
MSE Journal Articles
SCBE Journal Articles

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