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Title: The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering
Authors: Pasula, Rupali Reddy
Lim, Sierin 
Ghadessy, Farid J.
Sana, Barindra
Keywords: Engineering::Bioengineering
Issue Date: 2022
Source: Pasula, R. R., Lim, S., Ghadessy, F. J. & Sana, B. (2022). The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering. Engineering Biology, 6(1), 17-22.
Project: NRF-CRP22-2019-0005
Journal: Engineering Biology
Abstract: Plastic pollution in diverse terrestrial and marine environments is a widely recognised and growing problem. Bio-recycling and upcycling of plastic waste is a potential solution to plastic pollution, as these processes convert plastic waste into useful materials. Polyethylene terephthalate (PET) is the most abundant plastic waste, and this material can be degraded by a class of recently discovered bacterial esterase enzymes known as PET hydrolases (PETase). Investigations of the enzymatic hydrolysis of diverse PET molecules have clearly revealed that the biodegradability of various PET substrates depends on both their chemical structure and physical properties, including polymer length, crystallinity, glass transition temperature, surface area, and surface charge. This review summarises the known impacts of crystallinity and other physical properties on enzymatic PET hydrolysis.
ISSN: 2398-6182
DOI: 10.1049/enb2.12018
Schools: School of Chemical and Biomedical Engineering 
Rights: © 2022 The Authors. Engineering Biology published by John Wiley & Sons Ltd on behalf of The Institution of Engineering and Technology. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

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