Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/159278
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dc.contributor.authorLee, Brian Juin Hsienen_US
dc.contributor.authorShelat, Vishal Girishchandraen_US
dc.date.accessioned2022-06-10T01:20:35Z-
dc.date.available2022-06-10T01:20:35Z-
dc.date.issued2021-
dc.identifier.citationLee, B. J. H. & Shelat, V. G. (2021). Spleen angiosarcoma: a world review. Expert Review of Gastroenterology & Hepatology, 15(10), 1115-1141. https://dx.doi.org/10.1080/17474124.2021.1945920en_US
dc.identifier.issn1747-4124en_US
dc.identifier.urihttps://hdl.handle.net/10356/159278-
dc.description.abstractIntroduction: Spleen angiosarcoma (SA) is a rare malignant neoplasm that arises from the splenic vascular endothelium, with only around 300 cases reported to date. Due to a limited number of reported cases, there is a paucity of data and a lack of understanding of its presentation, diagnosis, and management. In this study, we aim to provide a comprehensive review of SA. Areas covered: On 27 February 2021, a literature search was done in PubMed and Embase database. The search yielded 122 articles involving 205 patients. The focus was on patient demographics, risk factors, clinical presentations, investigation results, preliminary diagnoses, therapies provided, and patient outcomes. These factors were analyzed to identify possible risk factors, diagnostic modalities, and therapeutic principles that were not mentioned before. Expert opinion: The clinical presentation or investigation results of patients with SA are often nonspecific. Hence, they may not be sufficient to clinch the diagnosis of SA if used alone. The authors recommend a triple assessment of clinical examination, imaging findings, and pathology to diagnose SA with high accuracy. Splenectomy should be the mainstay of management, with chemotherapy and radiotherapy considered as adjuncts, especially in the presence of metastases.en_US
dc.language.isoenen_US
dc.relation.ispartofExpert Review of Gastroenterology & Hepatologyen_US
dc.rights© 2021 Informa UK Limited, trading as Taylor & Francis Group. All rights reserved.en_US
dc.subjectScience::Medicineen_US
dc.titleSpleen angiosarcoma: a world reviewen_US
dc.typeJournal Articleen
dc.contributor.schoolLee Kong Chian School of Medicine (LKCMedicine)en_US
dc.identifier.doi10.1080/17474124.2021.1945920-
dc.identifier.pmid15-
dc.identifier.scopus2-s2.0-85111593988-
dc.identifier.issue10en_US
dc.identifier.volume15en_US
dc.identifier.spage1115en_US
dc.identifier.epage1141en_US
dc.subject.keywordsAngiosarcomaen_US
dc.subject.keywordsAspleniaen_US
item.grantfulltextnone-
item.fulltextNo Fulltext-
Appears in Collections:LKCMedicine Journal Articles

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