Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/159351
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dc.contributor.authorZhang, Ruochongen_US
dc.contributor.authorLuo, Yunqien_US
dc.contributor.authorJin, Haoranen_US
dc.contributor.authorGao, Feien_US
dc.contributor.authorZheng, Yuanjinen_US
dc.date.accessioned2022-06-15T01:56:01Z-
dc.date.available2022-06-15T01:56:01Z-
dc.date.issued2020-
dc.identifier.citationZhang, R., Luo, Y., Jin, H., Gao, F. & Zheng, Y. (2020). Time-domain photoacoustic waveform analysis for glucose measurement. Analyst, 145(24), 7964-7972. https://dx.doi.org/10.1039/d0an01678ken_US
dc.identifier.issn0003-2654en_US
dc.identifier.urihttps://hdl.handle.net/10356/159351-
dc.description.abstractPhotoacoustic (PA) effect is the product of light-ultrasound interactions and its time-domain waveform contains rich information. Besides optical absorption, the PA waveform inherently consists of other mechanical and thermal properties of the sample. They also have correlation with the target composition but have not been utilized in conventional PA spectroscopy. In this article, we propose a new concept named time-domain photoacoustic waveform spectroscopy (tPAWS) for chemical component quantification. It employs multiple variables inherently contained in the PA waveform excited by a single wavelength laser to extract informative features. The demonstration of glucose measurement in human blood serum (HBS) shows superior sensitivity and accuracy enhancement, compared to conventional amplitude-based PA measurement and NIR spectroscopy. Thanks to the sensitivity and accuracy of tPAWS, multiple wavelength sources and complex instrumentation used in conventional spectroscopic sensing methods can be avoided. TPAWS, as a novel physics-inspired sensing method, shows great potential for complementing or surpassing the current spectroscopic methods as a new sensing technique for chemical analysis.en_US
dc.language.isoenen_US
dc.relation.ispartofAnalysten_US
dc.rights© 2020 The Royal Society of Chemistry. All rights reserved.en_US
dc.subjectEngineering::Electrical and electronic engineeringen_US
dc.titleTime-domain photoacoustic waveform analysis for glucose measurementen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Electrical and Electronic Engineeringen_US
dc.identifier.doi10.1039/d0an01678k-
dc.identifier.pmid33034591-
dc.identifier.scopus2-s2.0-85099155599-
dc.identifier.issue24en_US
dc.identifier.volume145en_US
dc.identifier.spage7964en_US
dc.identifier.epage7972en_US
dc.subject.keywordsGlucoseen_US
dc.subject.keywordsPhotoacoustic Spectroscopyen_US
item.grantfulltextnone-
item.fulltextNo Fulltext-
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