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Title: Antimicrobial carbohydrate-based macromolecules: their structures and activities
Authors: Xu, Yuan
Zhang, Hongbin
Liu, Xue-Wei
Keywords: Science::Chemistry
Issue Date: 2020
Source: Xu, Y., Zhang, H. & Liu, X. (2020). Antimicrobial carbohydrate-based macromolecules: their structures and activities. Journal of Organic Chemistry, 85, 15827-15836.
Project: RG120/18
Journal: Journal of Organic Chemistry
Abstract: Emerging drug resistance is creating an urgent demand for new antimicrobial therapeutics. Besides the development of conventional antibiotics, antimicrobial agents with novel mechanisms have attracted great attention, such as antimicrobial peptides and polymers. Interactions between carbohydrates and proteins on microbes are believed to be the first step of pathogenesis. Thus, considerable efforts have been made on the development of carbohydrate-containing molecules in antimicrobial research. Recent progress of glycosylated macromolecules for antimicrobial applications has been discussed with an emphasis on synthetic glycosylated materials.
ISSN: 0022-3263
DOI: 10.1021/acs.joc.0c01597
Schools: School of Physical and Mathematical Sciences 
Rights: © 2020 American Chemical Society. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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