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Title: Water-tolerant ortho-acylation of phenols
Authors: Tian, Jie-Sheng
He, Yu
Gao, Zhi-Yuan
Liu, Xu
Dong, Shuang-Feng
Wu, Peng
Loh, Teck-Peng
Keywords: Science::Chemistry
Issue Date: 2021
Source: Tian, J., He, Y., Gao, Z., Liu, X., Dong, S., Wu, P. & Loh, T. (2021). Water-tolerant ortho-acylation of phenols. Organic Letters, 23(16), 6594-6598.
Project: M4012045.110 (RG12/18-S)
Journal: Organic Letters
Abstract: A metal-free, water-tolerant, and one-pot process for ortho-acylation of phenols promoted by the iodine source/hydrogen peroxide system has been developed. This transformation undergoes ether formation, iodocyclization, C-C bond cleavage, and oxidative hydrolysis in a one-step manner, which is supported by control experiments.
ISSN: 1523-7060
DOI: 10.1021/acs.orglett.1c02583
Schools: School of Physical and Mathematical Sciences 
Rights: © 2021 American Chemical Society. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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