Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/160848
Title: Asthma prescribing according to Arg16Gly beta-2 genotype: a randomised trial in adolescents
Authors: Ruffles, Tom
Jones, Christina J.
Palmer, Colin
Turner, Steve
Grigg, Jonathan
Tavendale, Roger
Hogarth, Fiona
Rauchhaus, Petra
Pilvinyte, Kristina
Hannah, Romanie
Smith, Helen Elizabeth
Littleford, Roberta
Lipworth, Brian
Mukhopadhyay, Somnath
Keywords: Science::Medicine
Issue Date: 2021
Source: Ruffles, T., Jones, C. J., Palmer, C., Turner, S., Grigg, J., Tavendale, R., Hogarth, F., Rauchhaus, P., Pilvinyte, K., Hannah, R., Smith, H. E., Littleford, R., Lipworth, B. & Mukhopadhyay, S. (2021). Asthma prescribing according to Arg16Gly beta-2 genotype: a randomised trial in adolescents. European Respiratory Journal, 58(2), 2004107-. https://dx.doi.org/10.1183/13993003.04107-2020
Journal: European Respiratory Journal
Abstract: The A allele of rs1042713 (Arg16 amino acid) in the β2-adrenoreceptor is associated with poor response to long-acting β2-agonist (LABA) in young people with asthma. Our aim was to assess whether the prescribing of second-line controller with LABA or a leukotriene receptor antagonist according to Arg16Gly genotype would result in improvements in Pediatric Asthma-Related Quality of Life Questionnaire (PAQLQ).
URI: https://hdl.handle.net/10356/160848
ISSN: 0903-1936
DOI: 10.1183/13993003.04107-2020
Schools: Lee Kong Chian School of Medicine (LKCMedicine) 
Rights: © 2021 The authors. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:LKCMedicine Journal Articles

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