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Title: The versatility of carbohydrates in antimicrobial applications
Authors: Xu, Yuan
Liu, Xue-Wei
Keywords: Science::Chemistry
Issue Date: 2020
Source: Xu, Y. & Liu, X. (2020). The versatility of carbohydrates in antimicrobial applications. Journal of the Chinese Chemical Society, 67(12), 2204-2207.
Project: RG120/18
Journal: Journal of the Chinese Chemical Society
Abstract: The worsening situation of global drug resistance is urgently demanding for novel antimicrobial agents. Considerable efforts have been concentrated on developing new antibacterial therapies with new mode of actions, exerting no selective pressure on bacterial mutation, and minimizing toxicity to host cells. In this context, active targeting can greatly contribute to selectivity between pathogens and mammalian cells in which carbohydrates, playing important roles in numerous biological processes, can be employed as targeting ligands or “trojan horse.” This short account has discussed the recent results of carbohydrate-based antimicrobial agents developed by our group. Other excellent works by other scientists and possible directions in the future are also discussed.
ISSN: 0009-4536
DOI: 10.1002/jccs.202000356
Schools: School of Physical and Mathematical Sciences 
Rights: © 2020 The Chemical Society Located in Taipei & Wiley-VCH GmbH. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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