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Title: Supramolecular adhesive hydrogels for tissue engineering applications
Authors: Zhao, Yue
Song, Shanliang
Ren, Xiangzhong
Zhang, Junmin
Lin, Quan
Zhao, Yanli
Keywords: Science::Chemistry::Biochemistry
Issue Date: 2022
Source: Zhao, Y., Song, S., Ren, X., Zhang, J., Lin, Q. & Zhao, Y. (2022). Supramolecular adhesive hydrogels for tissue engineering applications. Chemical Reviews, 122(6), 5604-5640.
Project: A20E5c0081 
Journal: Chemical Reviews
Abstract: Tissue engineering is a promising and revolutionary strategy to treat patients who suffer the loss or failure of an organ or tissue, with the aim to restore the dysfunctional tissues and enhance life expectancy. Supramolecular adhesive hydrogels are emerging as appealing materials for tissue engineering applications owing to their favorable attributes such as tailorable structure, inherent flexibility, excellent biocompatibility, near-physiological environment, dynamic mechanical strength, and particularly attractive self-adhesiveness. In this review, the key design principles and various supramolecular strategies to construct adhesive hydrogels are comprehensively summarized. Thereafter, the recent research progress regarding their tissue engineering applications, including primarily dermal tissue repair, muscle tissue repair, bone tissue repair, neural tissue repair, vascular tissue repair, oral tissue repair, corneal tissue repair, cardiac tissue repair, fetal membrane repair, hepatic tissue repair, and gastric tissue repair, is systematically highlighted. Finally, the scientific challenges and the remaining opportunities are underlined to show a full picture of the supramolecular adhesive hydrogels. This review is expected to offer comparative views and critical insights to inspire more advanced studies on supramolecular adhesive hydrogels and pave the way for different fields even beyond tissue engineering applications.
ISSN: 0009-2665
DOI: 10.1021/acs.chemrev.1c00815
Schools: School of Physical and Mathematical Sciences 
Rights: © 2022 American Chemical Society. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
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