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Title: Chemical design principles of next-generation antiviral surface coatings
Authors: Wang, Nan
Ferhan, Abdul Rahim
Yoon, Bo Kyeong
Jackman, Joshua A.
Cho, Nam-Joon
Majima, Tetsuro
Keywords: Engineering::Chemical engineering
Issue Date: 2021
Source: Wang, N., Ferhan, A. R., Yoon, B. K., Jackman, J. A., Cho, N. & Majima, T. (2021). Chemical design principles of next-generation antiviral surface coatings. Chemical Society Reviews, 50(17), 9741-9765.
Journal: Chemical Society Reviews
Abstract: The ongoing coronavirus disease 2019 (COVID-19) pandemic has accelerated efforts to develop high-performance antiviral surface coatings while highlighting the need to build a strong mechanistic understanding of the chemical design principles that underpin antiviral surface coatings. Herein, we critically summarize the latest efforts to develop antiviral surface coatings that exhibit virus-inactivating functions through disrupting lipid envelopes or protein capsids. Particular attention is focused on how cutting-edge advances in material science are being applied to engineer antiviral surface coatings with tailored molecular-level properties to inhibit membrane-enveloped and non-enveloped viruses. Key topics covered include surfaces functionalized with organic and inorganic compounds and nanoparticles to inhibit viruses, and self-cleaning surfaces that incorporate photocatalysts and triplet photosensitizers. Application examples to stop COVID-19 are also introduced and demonstrate how the integration of chemical design principles and advanced material fabrication strategies are leading to next-generation surface coatings that can help thwart viral pandemics and other infectious disease threats.
ISSN: 0306-0012
DOI: 10.1039/d1cs00317h
Schools: School of Materials Science and Engineering 
Rights: © 2021 The Royal Society of Chemistry. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
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