Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/162011
Full metadata record
DC FieldValueLanguage
dc.contributor.authorKali, Suresh Kumaren_US
dc.contributor.authorDröge, Peteren_US
dc.contributor.authorMurugan, Priyatharshinien_US
dc.date.accessioned2022-09-29T05:06:38Z-
dc.date.available2022-09-29T05:06:38Z-
dc.date.issued2021-
dc.identifier.citationKali, S. K., Dröge, P. & Murugan, P. (2021). Interferon β, an enhancer of the innate immune response against SARS-CoV-2 infection. Microbial Pathogenesis, 158, 105105-. https://dx.doi.org/10.1016/j.micpath.2021.105105en_US
dc.identifier.issn0882-4010en_US
dc.identifier.urihttps://hdl.handle.net/10356/162011-
dc.description.abstractCOVID-19 exhibits a global health threat among the elderly and the population with underlying health conditions. During infection, the host's innate immune response acts as a frontline of defense by releasing cytokines such as type I interferon (IFN α and β) thereby initiating antiviral activity. However, this particular interferon response is interrupted by factors such as SARS-CoV-2 non-structural proteins, aging, diabetes, and germ-line errors eventually making the host more susceptible to illness. Therefore, enhancing the host's innate immune response by administering type I IFN could be an effective treatment against COVID-19. Here, we highlight the importance of innate immune response and the role of IFN β monotherapy against COVID-19.en_US
dc.language.isoenen_US
dc.relation.ispartofMicrobial Pathogenesisen_US
dc.rights© 2021 Elsevier Ltd. All rights reserved.en_US
dc.subjectScience::Biological sciencesen_US
dc.titleInterferon β, an enhancer of the innate immune response against SARS-CoV-2 infectionen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Biological Sciencesen_US
dc.identifier.doi10.1016/j.micpath.2021.105105-
dc.identifier.pmid34311016-
dc.identifier.scopus2-s2.0-85111249287-
dc.identifier.volume158en_US
dc.identifier.spage105105en_US
dc.subject.keywordsCoronavirus Disease 2019en_US
dc.subject.keywordsSevere Acute Respiratory Syndromeen_US
item.grantfulltextnone-
item.fulltextNo Fulltext-
Appears in Collections:SBS Journal Articles

SCOPUSTM   
Citations 50

3
Updated on Jan 31, 2023

Web of ScienceTM
Citations 50

3
Updated on Jan 31, 2023

Page view(s)

25
Updated on Feb 3, 2023

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.