Please use this identifier to cite or link to this item:
Title: Multifunctional virus manipulation with large-scale arrays of all-dielectric resonant nanocavities
Authors: Shi, Yuzhi
Wu, Yongfeng
Chin, Lip Ke
Li, Zhenyu
Liu, Jingquan
Chen, Mu Ku
Wang, Shubo
Zhang, Yi
Liu, Patricia Yang
Zhou, Xiaohong
Cai, Hong
Jin, Wanzhen
Yu, Yefeng
Yu, Ruozhen
Huang, Wei
Yap, Peng Huat
Xiao, Limin
Ser, Wee
Nguyen, Thi Thanh Binh
Lin, Yu-Tsung
Wu, Pin Chieh
Liao, Jiayan
Wang, Fan
Chan, C.T.
Kivshar, Yuri
Tsai, Din Ping
Liu, Ai Qun
Keywords: Science::Medicine
Engineering::Electrical and electronic engineering
Issue Date: 2022
Source: Shi, Y., Wu, Y., Chin, L. K., Li, Z., Liu, J., Chen, M. K., Wang, S., Zhang, Y., Liu, P. Y., Zhou, X., Cai, H., Jin, W., Yu, Y., Yu, R., Huang, W., Yap, P. H., Xiao, L., Ser, W., Nguyen, T. T. B., ...Liu, A. Q. (2022). Multifunctional virus manipulation with large-scale arrays of all-dielectric resonant nanocavities. Laser and Photonics Reviews, 16(5), 2100197-.
Project: NRFCRP13-2014-01
Journal: Laser and Photonics Reviews
Abstract: Spatial manipulation of a precise number of viruses for host cell infection is essential for the extensive studies of virus pathogenesis and evolution. Albeit optical tweezers have been advanced to the atomic level via optical cooling, it is still challenging to efficiently trap and manipulate arbitrary number of viruses in an aqueous environment, being restricted by insufficient strength of optical forces and a lack of multifunctional spatial manipulation techniques. Here, by employing the virus hopping and flexibility of moving the laser position, multifunctional virus manipulation with a large trapping area is demonstrated, enabling single or massive (a large quantity of) virus transporting, positioning, patterning, sorting, and concentrating. The enhanced optical forces are produced by the confinement of light in engineered arrays of nanocavities by fine tuning of the interference resonances, and this approach allows trapping and moving viruses down to 40 nm in size. The work paves the way to efficient and precise manipulation of either single or massive groups of viruses, opening a wide range of novel opportunities for virus pathogenesis and inhibitor development at the single-virus level.
ISSN: 1863-8880
DOI: 10.1002/lpor.202100197
Rights: © 2022 Wiley-VCH GmbH. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:EEE Journal Articles
LKCMedicine Journal Articles
MAE Journal Articles

Citations 50

Updated on Nov 29, 2022

Web of ScienceTM
Citations 50

Updated on Dec 1, 2022

Page view(s)

Updated on Dec 3, 2022

Google ScholarTM




Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.