Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/162599
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wu, Fuqing | en_US |
dc.contributor.author | Lee, Wei Lin | en_US |
dc.contributor.author | Chen, Hongjie | en_US |
dc.contributor.author | Gu, Xiaoqiong | en_US |
dc.contributor.author | Chandra, Franciscus | en_US |
dc.contributor.author | Armas, Federica | en_US |
dc.contributor.author | Xiao, Amy | en_US |
dc.contributor.author | Leifels, Mats | en_US |
dc.contributor.author | Rhode, Steven F. | en_US |
dc.contributor.author | Wuertz, Stefan | en_US |
dc.contributor.author | Thompson, Janelle | en_US |
dc.contributor.author | Alm, Eric J. | en_US |
dc.date.accessioned | 2022-11-01T01:08:02Z | - |
dc.date.available | 2022-11-01T01:08:02Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Wu, F., Lee, W. L., Chen, H., Gu, X., Chandra, F., Armas, F., Xiao, A., Leifels, M., Rhode, S. F., Wuertz, S., Thompson, J. & Alm, E. J. (2022). Making waves: wastewater surveillance of SARS-CoV-2 in an endemic future. Water Research, 219, 118535-. https://dx.doi.org/10.1016/j.watres.2022.118535 | en_US |
dc.identifier.issn | 0043-1354 | en_US |
dc.identifier.uri | https://hdl.handle.net/10356/162599 | - |
dc.description.abstract | Wastewater-based surveillance (WBS) has been widely used as a public health tool to monitor the emergence and spread of SARS-CoV-2 infections in populations during the COVID-19 pandemic. Coincident with the global vaccination efforts, the world is also enduring new waves of SARS-CoV-2 variants. Reinfections and vaccine breakthroughs suggest an endemic future where SARS-CoV-2 continues to persist in the general population. In this treatise, we aim to explore the future roles of wastewater surveillance. Practically, WBS serves as a relatively affordable and non-invasive tool for mass surveillance of SARS-CoV-2 infection while minimizing privacy concerns, attributes that make it extremely suited for its long-term usage. In an endemic future, the utility of WBS will include 1) monitoring the trend of viral loads of targets in wastewater for quantitative estimate of changes in disease incidence; 2) sampling upstream for pinpointing infections in neighborhoods and at the building level; 3) integrating wastewater and clinical surveillance for cost-efficient population surveillance; and 4) genome sequencing wastewater samples to track circulating and emerging variants in the population. We further discuss the challenges and future developments of WBS to reduce inconsistencies in wastewater data worldwide, improve its epidemiological inference, and advance viral tracking and discovery as a preparation for the next viral pandemic. | en_US |
dc.description.sponsorship | Ministry of Education (MOE) | en_US |
dc.description.sponsorship | National Research Foundation (NRF) | en_US |
dc.language.iso | en | en_US |
dc.relation | NRF2019-THE001-0003a | en_US |
dc.relation.ispartof | Water Research | en_US |
dc.rights | © 2022 Published by Elsevier Ltd. All rights reserved. | en_US |
dc.subject | Engineering::Environmental engineering | en_US |
dc.title | Making waves: wastewater surveillance of SARS-CoV-2 in an endemic future | en_US |
dc.type | Journal Article | en |
dc.contributor.school | School of Civil and Environmental Engineering | en_US |
dc.contributor.school | Asian School of the Environment | en_US |
dc.contributor.organization | Campus for Research Excellence and Technological Enterprise (CREATE) | en_US |
dc.contributor.research | Singapore Centre for Environmental Life Sciences and Engineering (SCELSE) | en_US |
dc.identifier.doi | 10.1016/j.watres.2022.118535 | - |
dc.identifier.pmid | 35605390 | - |
dc.identifier.scopus | 2-s2.0-85130847224 | - |
dc.identifier.volume | 219 | en_US |
dc.identifier.spage | 118535 | en_US |
dc.subject.keywords | Wastewater Surveillance | en_US |
dc.subject.keywords | SARS-CoV-2 | en_US |
dc.description.acknowledgement | This work was supported by the MIT Center for Microbiome Informatics and Therapeutics, funding from the Massachusetts Consortium on Pathogen Readiness (MassCPR) and China Evergrande Group (EJA), the National Research Foundation, Prime Minister’s Office, Singapore, under its Campus for Research Excellence and Technological Enterprise (CREATE) program funding to the Singapore-MIT Alliance for Research and Technology (SMART) Antimicrobial Resistance Interdisciplinary Research Group (AMR IRG), the Intra-CREATE Thematic Grant (Cities) grant NRF2019-THE001–0003a to JT and EJA and funding from the Singapore Ministry of Education and National Research Foundation through an RCE award to Singapore centre for Environmental Life Sciences Engineering (SCELSE) to SW and JT. FW is supported by the Faculty Startup funding from the Center of Infectious Diseases at UTHealth, the UT system Rising STARs award, and the Texas Epidemic Public Health Institute (TEPHI), which is housed within and supported administratively by The University of Texas Health Science Center at Houston (UTHealth). | en_US |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
Appears in Collections: | ASE Journal Articles CEE Journal Articles SCELSE Journal Articles |
SCOPUSTM
Citations
20
28
Updated on Mar 23, 2024
Web of ScienceTM
Citations
20
18
Updated on Oct 28, 2023
Page view(s)
103
Updated on Mar 28, 2024
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.