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Title: Increased consumption of unsaturated fatty acids improves body composition in a hypercholesterolemic Chinese population
Authors: Haldar, Sumanto
Ponnalagu, Shalini
Osman, Farhana
Tay, Shia Lyn
Wong, Long Hui
Jiang, Yuan Rong
Leow, Melvin Khee-Shing
Henry, Christiani Jeyakumar
Keywords: Science::Medicine
Issue Date: 2022
Source: Haldar, S., Ponnalagu, S., Osman, F., Tay, S. L., Wong, L. H., Jiang, Y. R., Leow, M. K. & Henry, C. J. (2022). Increased consumption of unsaturated fatty acids improves body composition in a hypercholesterolemic Chinese population. Frontiers in Nutrition, 9, 869351-.
Journal: Frontiers in Nutrition 
Abstract: While an increase in fat intake and the resulting excess calorie intake are implicated in weight gain, different fat types exert variable effects on body composition, with unsaturated fats showing favorable effects on body composition in Western population. Whether and to what extent these associations apply to Asian population have not been established. We investigated the effects of two separate Asian-based oil blends, rich in unsaturated fats, made from refined rice bran, sesame, and flaxseed oils, in comparison with refined olive oil, on body composition using dual-energy X-ray absorptiometry (DXA), from an 8-week, parallel design, randomized trial in 66 men (58.7 ± 5.71 years old, 23.0 ± 2.38 kg/m2) and 69 postmenopausal women (59.1 ± 5.34 years old, 21.7 ± 2.52 kg/m2), with borderline hypercholesterolemia. Despite increases in mean daily intakes of total energy (approximately +400 kcal/day, female, and approximately +240 kcal/day, male), as well as increases in percentage of calories from fats and proteins and decreases in percentage of calories from carbohydrates during the dietary intervention period, there were no significant changes in total body fat mass in both genders and also in all treatment groups. While total body weight increased slightly (0.36 ± 0.12 kg, p = 0.005) in women during intervention, this was mainly due to gain in lean mass (0.38 ± 0.081 kg, p < 0.0001). Correspondingly, there were reductions in total body fat (%), android fat (%), and gynoid fat (%) in women. No significant differences between the 3 intervention oil types were found in any of the measured parameters in either gender. Increasing relative intakes of unsaturated fats may prevent fat mass gain and circumvent muscle mass loss associated with menopause in older Asian women. Long-term studies are needed to confirm findings. This study had been registered on (Identifier No.: NCT03964857,
ISSN: 2296-861X
DOI: 10.3389/fnut.2022.869351
Schools: Lee Kong Chian School of Medicine (LKCMedicine) 
Organisations: Singapore Institute for Clinical Sciences, A*STAR
Tan Tock Seng Hospital
Rights: © 2022 Haldar, Ponnalagu, Osman, Tay, Wong, Jiang, Leow and Henry. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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