Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/163031
Title: The total synthesis of raistrickindole A
Authors: Pham, Thang Loi
Sae-Lao, Patcharaporn
Toh, Hannah Hui Min
Csókás, Dániel
Bates, Roderick Wayland
Keywords: Science::Chemistry
Issue Date: 2022
Source: Pham, T. L., Sae-Lao, P., Toh, H. H. M., Csókás, D. & Bates, R. W. (2022). The total synthesis of raistrickindole A. Journal of Organic Chemistry. https://dx.doi.org/10.1021/acs.joc.2c02033
Project: NRF-CRP18-2017-01
Journal: Journal of Organic Chemistry
Abstract: The total synthesis of raistrickindole A has been achieved, thereby confirming the proposed structure as an N-hydroxylated DKP. In the first but less selective approach, the DKP was built up by cyclization of a diastereoisomerically mixed N-hydroxylated dipeptide. In the second approach, the same DKP was constructed stereoselectively by the intramolecular Mitsunobu reaction of a hydroxamic acid. The synthesis was completed by a stereoselective oxidative cyclization.
URI: https://hdl.handle.net/10356/163031
ISSN: 0022-3263
DOI: 10.1021/acs.joc.2c02033
Rights: This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Organic Chemistry, copyright © 2022 American Chemical Society, after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.joc.2c02033.
Fulltext Permission: embargo_20231118
Fulltext Availability: With Fulltext
Appears in Collections:CCEB Journal Articles

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