Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/163076
Title: An open-label, single-arm pilot study of tocotrienols supplementation on improving memory and attention in healthy young adults
Authors: Par, Rae Yi Xin
Teo, Cheryl Wei Ling
Tan, Javier Joon Kiat
Ung, Yee Wei
Heng, Kiang Soon
Hang, Li Ting
Yeo, Mervyn
Yap, Wei Ney
Keywords: Science::Biological sciences
Issue Date: 2022
Source: Par, R. Y. X., Teo, C. W. L., Tan, J. J. K., Ung, Y. W., Heng, K. S., Hang, L. T., Yeo, M. & Yap, W. N. (2022). An open-label, single-arm pilot study of tocotrienols supplementation on improving memory and attention in healthy young adults. Journal of Functional Foods, 92, 105055-. https://dx.doi.org/10.1016/j.jff.2022.105055
Journal: Journal of Functional Foods
Abstract: This study aimed to investigate the beneficial effects of tocotrienols (T3) supplementation on one's attention and memory. Eleven healthy subjects were enrolled to receive placebo followed by T3 in 6 weeks. Psychomotor Vigilance Task (PVT) and Digit Span Test (DST) were used to access subjects’ sustained attention and working memory. Electroencephalogram (EEG) was used to examine the brainwave activity. T3 supplementation significantly improved the memory of the subjects in relative to the baseline as measured by average mean span for forward and reverse DST. Notably, a significant memory enhancement for T3 over placebo was observed. Subjects who consumed T3 have shown faster reaction as compared to placebo as assessed by PVT. T3 supplementation showed an overall reduction in alpha and low-beta power in comparison to placebo, indicating T3 promoted a higher neural efficacy. T3 supplementation may act as a potential nootropic in improving the mental performance and cognitive activity.
URI: https://hdl.handle.net/10356/163076
ISSN: 1756-4646
DOI: 10.1016/j.jff.2022.105055
Rights: © 2022 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SBS Journal Articles

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