Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/163849
Title: An update on adrenocortical cell lines of human origin
Authors: Sigala, Sandra
Rossini, Elisa
Abate, Andrea
Tamburello, Mariangela
Bornstein, Stefan R.
Hantel, Constanze
Keywords: Science::Medicine
Issue Date: 2022
Source: Sigala, S., Rossini, E., Abate, A., Tamburello, M., Bornstein, S. R. & Hantel, C. (2022). An update on adrenocortical cell lines of human origin. Endocrine, 77(3), 432-437. https://dx.doi.org/10.1007/s12020-022-03112-w
Journal: Endocrine
Abstract: Adrenocortical carcinoma (ACC) is a rare, heterogenous and highly malignant disease. Management of ACC is dependent on disease stage with complete surgical resection as the only potentially curative option. However, advanced, un-resectable, metastatic stages and also recurrences often require systemic treatments, which are unfortunately nowadays still unsatisfactory. The scarcity of preclinical models reflecting patient heterogeneities and furthermore drug-resistant phenotypes, has hampered the progress and development of new therapies in recent years. In this review, we provide an overview on the classical models and substantial progress which has been made over the last years in context of this aggressive disease.
URI: https://hdl.handle.net/10356/163849
ISSN: 1355-008X
DOI: 10.1007/s12020-022-03112-w
Rights: © The Author(s) 2022. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons. org/licenses/by/4.0/.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

Files in This Item:
File Description SizeFormat 
s12020-022-03112-w.pdf531.5 kBAdobe PDFView/Open

SCOPUSTM   
Citations 50

2
Updated on Feb 2, 2023

Web of ScienceTM
Citations 50

2
Updated on Feb 4, 2023

Page view(s)

26
Updated on Feb 6, 2023

Download(s)

3
Updated on Feb 6, 2023

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.