Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/163917
Title: Rapid construction of green nanopesticide delivery systems using sophorolipids as surfactants by flash nanoprecipitation
Authors: Ma, Enguang
Chen, Kai
Sun, Liang
Fu, Zhinan
Guo, Jiangtao
Liu, Jichang
Zhao, Jigang
Liu, Zhiyong
Lei, Zhigang
Li, Li
Hu, Xiao
Guo, Xuhong
Keywords: Engineering::Chemical engineering
Issue Date: 2022
Source: Ma, E., Chen, K., Sun, L., Fu, Z., Guo, J., Liu, J., Zhao, J., Liu, Z., Lei, Z., Li, L., Hu, X. & Guo, X. (2022). Rapid construction of green nanopesticide delivery systems using sophorolipids as surfactants by flash nanoprecipitation. Journal of Agricultural and Food Chemistry, 70(16), 4912-4920. https://dx.doi.org/10.1021/acs.jafc.2c00743
Journal: Journal of Agricultural and Food Chemistry
Abstract: Green delivery carriers of nanopesticides, like sophorolipid biosurfactants, are of great significance to reduce environmental pollution and promote sustainable agricultural development. However, the molecular diversity of an unisolated sophorolipid mixture with almost unpredictable self-assembly properties has limited the in-depth study of its structure-activity relationship and hindered the development of green pesticide delivery systems. In this work, the acidic and lactonic sophorolipids were successfully separated from the sophorolipid mixture through silica gel column chromatography. A series of cost-effective green nanopesticides loaded with lambda-cyhalothrin (LC) were rapidly fabricated based on a combination of the acidic and lactonic sophorolipids as surfactants by flash nanoprecipitation. The effects of the acidic-to-lactonic ratio on particle size, drug loading capacity, and biological activity against Hyphantria cunea of LC-loaded nanoparticles were systematically investigated. The resultant nanopesticides exhibited a better insecticidal efficacy than a commercial emulsifiable concentrate formulation. This work opens up a novel strategy to construct scalable, cost-effective, and environmentally friendly nanopesticide systems.
URI: https://hdl.handle.net/10356/163917
ISSN: 0021-8561
DOI: 10.1021/acs.jafc.2c00743
Rights: © 2022 American Chemical Society. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:MSE Journal Articles

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