Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/16441
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dc.contributor.authorFerhan Putra
dc.date.accessioned2009-05-26T04:38:01Z
dc.date.available2009-05-26T04:38:01Z
dc.date.copyright2009en_US
dc.date.issued2009
dc.identifier.urihttp://hdl.handle.net/10356/16441
dc.description.abstractThis project focused on the preliminary development of a microfluidic flow-through module for an electrochemical deoxyribonucleic acid (DNA) sensor. The sensor shall replace a real-time polymerase chain reaction (RT-PCR) module currently integrated with a patented sample preparation kit developed at IBN suitable for point-of-care diagnosis. The development process involves three phases which includes a comparative study of different chip designs as well as fabrication techniques, an initial qualitative fluidics study followed by a quantitative characterization of the flow using actual reagents leading to a final optimization procedure and calibration. Through the first phase, it was observed that chips fabricated via photolithography yields better results than those fabricated via electron beam physical vapor deposition. Subsequent experimental results based on devices fabricated via photolithography presented herein have proven the promising operability of the flow system.en_US
dc.format.extent85 p.en_US
dc.language.isoenen_US
dc.rightsNanyang Technological University
dc.subjectDRNTU::Engineering::Chemical engineering::Biotechnologyen_US
dc.titleIntegration of amperometric electrochemical biosensor for detection of target nucleic acid in an automated sample preparation systemen_US
dc.typeFinal Year Project (FYP)en_US
dc.contributor.supervisorLi Changmingen_US
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.description.degreeBachelor of Engineering (Chemical and Biomolecular Engineering)en_US
dc.contributor.organizationA*STAR Institute of Bioengineering and Nanotechnologyen_US
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Appears in Collections:SCBE Student Reports (FYP/IA/PA/PI)
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