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Title: Development of water-based C-X bond formation reactions
Authors: Goh, Jeffrey
Keywords: Science::Chemistry::Organic chemistry::Organic synthesis
Issue Date: 2023
Publisher: Nanyang Technological University
Source: Goh, J. (2023). Development of water-based C-X bond formation reactions. Doctoral thesis, Nanyang Technological University, Singapore.
Project: 21702108 
M4012045.110 (RG12/18-S) 
Abstract: The push for conducting chemical syntheses under green conditions (metal-free, room temperature, non-toxic solvent, neutral pH, no column chromatography or liquid-liquid extraction etc.) has been gaining track in recent times. By achieving this goal, we could potentially replace traditional methods which are generally exorbitant and non-environmentally friendly, thereby reducing chemical waste and valuable resources. If successful, these green synthetic strategies can be readily applied to the (1) synthesis of pharmaceuticals, (2) one-pot multi-step synthesis and (3) biomolecules functionalization. With this goal in mind, we will be able to advance the discourse on green chemical syntheses. In this thesis, we are focused on the development of a toolbox of various green synthetic methods. Henceforth, we report the development of various catalyst-free C-X bond forming reactions under green or biocompatible conditions.
DOI: 10.32657/10356/164433
Schools: School of Chemistry, Chemical Engineering and Biotechnology
Rights: This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:CCEB Theses

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