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Title: Cardio-sarcopenia: a syndrome of concern in aging
Authors: Loh, De Rong
Tan, Ru-San
Lim, Wee Shiong
Koh, Angela S.
Keywords: Science::Medicine
Issue Date: 2022
Source: Loh, D. R., Tan, R., Lim, W. S. & Koh, A. S. (2022). Cardio-sarcopenia: a syndrome of concern in aging. Frontiers in Medicine, 9, 1027466-.
Project: MOH/NIC/HAIG03/2017 
Journal: Frontiers in Medicine
Abstract: Cardiac alterations in structure and function, namely, the left ventricle, have been intensely studied for decades, in association with aging. In recent times, there has been keen interest in describing myocardial changes that accompany skeletal muscle changes in older adults. Initially described as a cardio-sarcopenia syndrome where alterations in myocardial structure were observed particularly among older adults with skeletal muscle sarcopenia, investigations into this syndrome have spurred a fresh level of interest in the cardiac-skeletal muscle axis. The purpose of this perspective is to summarize the background for this "syndrome of concern," review the body of work generated by various human aging cohorts, and to explore future directions and opportunities for understanding this syndrome.
ISSN: 2296-858X
DOI: 10.3389/fmed.2022.1027466
Schools: Lee Kong Chian School of Medicine (LKCMedicine) 
Organisations: Tan Tock Seng Hospital
Rights: © 2022 Loh, Tan, Lim and Koh. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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