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Title: | Ellipsoidal magnetic mesoporous particles for targeted drug delivery. | Authors: | Chia, Daryl De Yuan. | Keywords: | DRNTU::Engineering::Chemical engineering::Biotechnology | Issue Date: | 2009 | Abstract: | Ellipsoidal rattle-type hollow particles with hematite (α-Fe2O3) spindles encapsulated in mesoporous silica shells have been fabricated by simultaneous sol-gel polymerization of tetraethoxysilane (TEOS) and n-octadecyltrimethoxysilane (C18TMS). A ring-shaped cavity was created between the iron oxide core and mesoporous silica shell by hydrothermal treatment followed by calcination to remove the organic groups. A mesoporous silica shell with randomly ordered mesopores and a cavity of up to 40 nm wide was created. The fabrication of ellipsoidal particles with α-Fe2O3 core-mesoporous silica shell was also attempted through surface templating with the cationic surfactant cetyltrimethylammonium bromide (CTAB) as a template. The synthesized particles were sub-optimal as the process used to fabricate the particles was not yet mature. | URI: | http://hdl.handle.net/10356/16482 | Schools: | School of Chemical and Biomedical Engineering | Rights: | Nanyang Technological University | Fulltext Permission: | restricted | Fulltext Availability: | With Fulltext |
Appears in Collections: | SCBE Student Reports (FYP/IA/PA/PI) |
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ChiaDeYuanDaryl09.pdf Restricted Access | 6.65 MB | Adobe PDF | View/Open |
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