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Title: Application of MCG-PTCC system on neo-cartilage regeneration
Authors: Jiang, Yuwei
Keywords: DRNTU::Engineering::Chemical engineering::Biotechnology
Issue Date: 2009
Abstract: This project aims to apply the advance fabricated micro-cavities gel (MCG) construct and the innovative phase transfer cell culture (PTCC) strategy to cartilage tissue engineering to realize the self-formation of the bone fide neo-cartilage tissue. The phenomenon called edge flourish (EF) is the underlying principle for successfully creating the MCG-PTCC system. The efficiency of the MCG-PTCC system on the cartilage regeneration is evaluated in terms of chondrocytes viability, development of the neo-cartilage tissue islets, related gene expression level, extracellular matrix (ECM) proteins production level. At the same time, the MCG-PTCC system is compared with the traditional therapeutic cell encapsulated hydrogel construct to prove its superiority.
Schools: School of Chemical and Biomedical Engineering 
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Student Reports (FYP/IA/PA/PI)

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