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https://hdl.handle.net/10356/168569| Title: | Variation of cerebrospinal fluid in specific regions regulates focality in transcranial direct current stimulation | Authors: | Kashyap, Rajan Bhattacharjee, Sagarika Bharath, Rose Dawn Venkatasubramanian, Ganesan Udupa, Kaviraja Bashir, Shahid Oishi, Kenichi Desmond, John E. Chen, Annabel Shen-Hsing Guan, Cuntai |
Keywords: | Science::Medicine | Issue Date: | 2022 | Source: | Kashyap, R., Bhattacharjee, S., Bharath, R. D., Venkatasubramanian, G., Udupa, K., Bashir, S., Oishi, K., Desmond, J. E., Chen, A. S. & Guan, C. (2022). Variation of cerebrospinal fluid in specific regions regulates focality in transcranial direct current stimulation. Frontiers in Human Neuroscience, 16, 952602-. https://dx.doi.org/10.3389/fnhum.2022.952602 | Project: | A20G8b0102 | Journal: | Frontiers in Human Neuroscience | Abstract: | Conventionally, transcranial direct current stimulation (tDCS) aims to focalize the current reaching the target region-of-interest (ROI). The focality can be quantified by the dose-target-determination-index (DTDI). Despite having a uniform tDCS setup, some individuals receive focal stimulation (high DTDI) while others show reduced focality ("non-focal"). The volume of cerebrospinal fluid (CSF), gray matter (GM), and white matter (WM) underlying each ROI govern the tDCS current distribution inside the brain, thereby regulating focality. | URI: | https://hdl.handle.net/10356/168569 | ISSN: | 1662-5161 | DOI: | 10.3389/fnhum.2022.952602 | Schools: | Lee Kong Chian School of Medicine (LKCMedicine) School of Computer Science and Engineering School of Social Sciences |
Research Centres: | Centre for Research and Development in Learning (CRADLE) | Rights: | © 2022 Kashyap, Bhattacharjee, Bharath, Venkatasubramanian, Udupa, Bashir, Oishi, Desmond, Chen and Guan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
| Appears in Collections: | LKCMedicine Journal Articles SCSE Journal Articles SSS Journal Articles |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| fnhum-16-952602.pdf | 4.37 MB | Adobe PDF |  View/Open |
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