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dc.contributor.authorZhang, Linjieen_US
dc.contributor.authorZhang, Qiaolinen_US
dc.contributor.authorZhang, Yanen_US
dc.contributor.authorArthur, Musinguzien_US
dc.contributor.authorTeo, Ee-Chonen_US
dc.contributor.authorBíró, Istvánen_US
dc.contributor.authorGu, Yaodongen_US
dc.identifier.citationZhang, L., Zhang, Q., Zhang, Y., Arthur, M., Teo, E., Bíró, I. & Gu, Y. (2022). The effect of concave-side intertransverse ligament laxity on the stress of AIS lumbar spine based on finite element method. Bioengineering, 9(12), 724-.
dc.description.abstract(1) Background: Scoliosis has the mechanical characteristic of asymmetric stress distribution, which is one of the reasons for the aggravation of scoliosis. Bracing therapy is the best treatment for AIS, but it is difficult and costly to operate. Is it possible to reduce pressure in the concave side by relaxing the ITL in the concave side of scoliosis, so as to improve the abnormal stress distribution of scoliosis? In this paper, a finite element method was used to simulate the effect of the relaxation of concave-side ITL on the stress of a lumbar spine with scoliosis, which provides some guidance for the treatment of scoliosis. (2) Methods: Using CT images of a patient with scoliosis whose Cobb Angle was 43° and Lordosis Angle was 45, a scoliosis lumbar was established, and Young's modulus of the ITL of the concave-side lumbar spine was reduced by 95% to simulate ligament relaxation. By comparing the stress condition of the model vertebral body with no ligament relaxation, the effect of concave-side ITL relaxation on the mechanical characteristics of scoliosis lumbar spine was explored. (3) Results: An effective and complete model of the lumbar spine was established. The concave ITL relaxed, which only had a great impact on the bending loads. After the ligament was relaxed, the stability of the spine was reduced. Stress concentration on the concave side of vertebrae and the IVD was aggravated. Under loads on the convex side, the maximum stress on the vertebral body and the IVD increased significantly, making lumbar vertebrae more vulnerable to injury. (4) Conclusions: Laxity of the ITL on the concave side of the AIS lumbar only affects the bending load. Laxity of the concave-side ligament will reduce the stability of the lumbar, aggravate the uneven stress distribution of scoliotic lumbar vertebrae, increase the risk of IVD injury, and be unfavorable for the scoliotic lumbar spine. Relaxation of the concave ITL alone is not an effective way to treat scoliosis.en_US
dc.rights© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// 4.0/).en_US
dc.titleThe effect of concave-side intertransverse ligament laxity on the stress of AIS lumbar spine based on finite element methoden_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.description.versionPublished versionen_US
dc.subject.keywordsIntertransverse Ligamenten_US
dc.subject.keywordsLigament Relaxationen_US
dc.description.acknowledgementThis study was supported by the Major Program of the National Science Foundation of China (19ZDA352), Zhejiang Province Key Research and Development Program of China (2021C03130), Zhejiang Provincial Natural Science Foundation of China for Distinguished Young Scholars (Grant No. LR22A02002), Philosophy and Social Sciences Project of Zhejiang Province, China (22QNYC10ZD, 22NDQN22YB), Educational science planning project of Zhejiang Province (2021SCG083), the Fundamental Research Funds for the Provincial Universities of Zhejiang (2021SCG283), the Fundamental Research Funds for the Provincial University of Zhejiang (SJWY2022014), Ningbo Natural Science Foundation (20221JCGY010532; 20221JCGY010607), and K.C Wong Magna Fund in Ningbo University.en_US
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