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https://hdl.handle.net/10356/182583| Title: | Allylation of lactol in water | Authors: | Zheng, Mengxue Gao, Wenxiu Zhang, Lei Yan, Kaiyu Zhang, Zhenguo Xie, Peizhong Loh, Teck-Peng |
Keywords: | Chemistry | Issue Date: | 2024 | Source: | Zheng, M., Gao, W., Zhang, L., Yan, K., Zhang, Z., Xie, P. & Loh, T. (2024). Allylation of lactol in water. Organic Letters, 26(47), 10201-10206. https://dx.doi.org/10.1021/acs.orglett.4c04189 | Project: | M21K2c0114 M22K9b0049 |
Journal: | Organic letters | Abstract: | We developed a water-promoted cross-coupling of 3-hydroxyisobenzofuran-1(3H)-ones and allylic boronates under biocompatible conditions. This approach facilitates the synthesis of diverse 3-allylic phthalides with high yields and exceptional selectivity in a metal-free manner. The versatility and practicality of this protocol underscore its significant potential for drug development and applications in medicinal chemistry. | URI: | https://hdl.handle.net/10356/182583 | ISSN: | 1523-7060 | DOI: | 10.1021/acs.orglett.4c04189 | Schools: | School of Physical and Mathematical Sciences | Rights: | © 2024 American Chemical Society. All rights reserved. | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
| Appears in Collections: | SPMS Journal Articles |
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