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dc.contributor.authorKam, Ee Fai
dc.description.abstractBiodegradable scaffolds for tissue engineering have been around for some years. However, none has been successful in engineering viable autologous blood vessels which have inner diameter less than 5mm and wall thickness of 100m. In this report, a tubular scaffold was fabricated using the electrospinning technique with a variety of parameters (weight percentage of polymer, voltage, flow rate, distance between needle tip to collector and speed of rotation of collector) to reach the dimensions of a small blood vessel. The biodegradable material used was Poly (L-lactide/ε-caprolactone) (PLC). In order to determine the optimal combination of these conditions, the scaffold was subjected to characterisation techniques such as Scanning Electron Microscopy (SEM), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Fourier-Transform Infrared Spectroscopy (FTIR) and Tensile Test. In this study, tubular scaffolds with very thin wall thickness of 42 micrometers were successfully made, with such tubes having tensile strength of 9.7MPa. The characterisation techniques also showed that PLC retained its thermal and chemical properties after electrospinning.en_US
dc.format.extent51 p.en_US
dc.rightsNanyang Technological University
dc.titleElectrospinning a small diameter tubular scaffold for tissue engineering blood vesselsen_US
dc.typeFinal Year Project (FYP)en_US
dc.contributor.schoolSchool of Materials Science and Engineeringen_US
dc.description.degreeBachelor of Engineering (Materials Engineering)en_US
dc.contributor.supervisor2Ng Kee Woeien_US
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Appears in Collections:MSE Student Reports (FYP/IA/PA/PI)
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