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https://hdl.handle.net/10356/35758
Title: | The role of the 235 kDA protein multigene family (py235) of the malaria parasite Plasmodium yoelii in invasion and host cell selection, virulence and immune evasion | Authors: | Jayasree Kaveri Iyer | Keywords: | DRNTU::Science::Biological sciences::Microbiology::Virology | Issue Date: | 2007 | Source: | Jayasree Kaveri Iyer. (2007). The role of the 235 kDA protein multigene family (py235) of the malaria parasite Plasmodium yoelii in invasion and host cell selection, virulence and immune evasion. Doctoral thesis, Nanyang Technological University, Singapore. | Abstract: | A key determinant of lethality in infections by the malaria parasite Plasmodium is the rapid multiplication cycles in the blood of an infected individual. The range of erythrocytes invaded is directly correlated to parasite virulence. The 235kDa protein multigene family (py235) has been previously implicated in mediating host cell selection and invasion in the rodent parasite Plasmodium yoelii. Using P. yoelii, we defined the copy number of py235 genes in parasites exhibiting different virulence. | Description: | 230 p. | URI: | https://hdl.handle.net/10356/35758 | DOI: | 10.32657/10356/35758 | Schools: | School of Biological Sciences | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | SBS Theses |
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SBS_THESES_3.pdf | 28.76 MB | Adobe PDF | View/Open |
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