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Title: Receptor mediated adhesion under external stimuli
Authors: Ang, Ming Sheng
Keywords: DRNTU::Engineering::Chemical engineering::Biotechnology
Issue Date: 2010
Abstract: Many studies have shown that Epigallocatechin-3-gallate (EGCG) from green tea, exhibits therapeutic effects that inhibits cancer invasion and metastasis and affects cell proliferation and death Since cell adhesion is an important process that regulates cell migration, the effects of EGCG on cell adhesion is investigated to understand more on its therapeutic effects. This study demonstrated that HepG2 cell cultured with increasing concentration of EGCG results in an increase in rate of adhesion contact area, degree of cell deformation and average adhesion energy of cell. The inhibition of cell migration by EGCG was also observed, which supports the evidence of therapeutic effects from EGCG.
Schools: School of Chemical and Biomedical Engineering 
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Student Reports (FYP/IA/PA/PI)

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