Fe(III)- and Au(I)-catalyzed cyclization of arene-alkynes.

Abstract

In this research report, Fe(III)- and Au(I)-catalyzed cyclizations of arene-alkynes were investigated. Au(I) catalyst has shown to be of very efficient catalytic activity for intramolecular hydroarylations of arene-alkynes with promising yields at mild conditions whether the alkyne is substituted by electron-withdrawing or electron-donating group. While Fe(III) was shown to be sensitive to the substitute on the alkyne moiety, electron-withdrawing group substituted alkynes did not proceed to cyclized products, but for the electron-donating group substituted arene-alkynes, Fe(III) catalyst showed as high efficiency as Au(I) catalyst.