Please use this identifier to cite or link to this item:
Title: Thermodynamics of short alanine-based peptides.
Authors: Guan, Ying Li.
Keywords: DRNTU::Science::Chemistry::Biochemistry
Issue Date: 2010
Abstract: Short alanine-based peptide forms approximately 80% helix content when formed under optimal conditions. Factors such as solvent concentration, pH, temperature and pressure play a part in determining the formation and stability of the helix content. The effect of temperature on protein folding is examined by performing a molecular dynamics simulation using AMBER force field, ff03, on 3K(I); acetyl-AAAAKAAAAKAAAAKA-amide at various temperatures to mimic an experimental study. The results are then characterized using root-mean-square deviation (RMSD), snapshots of the folding process, potential mean force (PMF) energy diagrams and secondary structure prediction using DSSP.
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Student Reports (FYP/IA/PA/PI)

Files in This Item:
File Description SizeFormat 
  Restricted Access
1.09 MBAdobe PDFView/Open

Page view(s)

checked on Sep 28, 2020


checked on Sep 28, 2020

Google ScholarTM


Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.